The San Francisco 49ers lost their star wide receiver, Brandon Aiyuk (knee), to a season-ending knee injury. This will ...

When Ricky Pearsall finally made his debut for the San Francisco 49ers in Week 7, it felt like a special moment not just for fans of the red and gold but of the NFL, period. A first-round pick, fresh ...

Niners wide receiver Deebo Samuel was released from the hospital Tuesday afternoon, a source told ESPN. He had been ...

Chad Reuter provides a look at the updated 2025 NFL Draft order for Round 1 along with needs for every team. Which pick is ...

Bye weeks are on a ... bye ... in Week 8, which means we've got a full 16-game slate of matchups on the horizon — ...

San Francisco 49ers rookie wide receiver Ricky Pearsall battled back from a gunshot wound he sustained in late August to make ...

San Francisco 49ers wide receiver Brandon Aiyuk (11) is hit by Kansas City Chiefs cornerback Trent McDuffie, left, and safety ...

SAN FRANCISCO - 49ers wide-receiver Brandon Aiyuk is out for the season, according to the team. The team's head coach Kyle ...

The San Francisco 49ers were already reeling from Monday's bad news that wide receiver Brandon Aiyuk was out for the season ...

When the Dallas Cowboys travel to face the San Francisco 49ers in Week 8, the 49ers may be without another one of their key offensive weapons.

Brandon Aiyuk suffers potential season-ending ACL tear, dealing a major blow to the 49ers' receiving corps. Ricky Pearsall ...

Here are your top 49ers storylines for Monday, October 21st.